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Craft S, Baker LD, Montine TJ, Minoshima S, Watson GS, Claxton A, et al

Patients tolerating once-daily GLP-1 receptor agonist therapy at the maximal therapeutic dose should start a once-weekly GLP-1 receptor agonist the day after their last dose of once-daily medication
Accordingly, one of the most remarkable central effects of GLP-1R signaling occurs in neuronal populations involved in the control of caloric intake by promoting anorexigenic effects

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& McCarty, D
