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Those in the higher dose group were also significantly more likely to reach weight reductions of up to 20% of their waist circumference (a clinically meaningful measure of cardiometabolic risk) and improve their HbA1C (a measure of blood sugar control) compared with the other two groups

[,] Since 2016, GLP-1RAs, approved for type 2 diabetes mellitus (T2DM) and obesity, have also shown cardiovascular safety

Reductions in heart failure 3 3

Image courtesy of Svetlana Mojsov, taken from her personal lab notebooks