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Key differences between the two compounds Semaglutide versus tirzepatide is a broader topic covered in depth elsewhere, but when it comes to the niacinamide additive specifically: The niacinamide serves the same purpose in both compounds

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Furthermore, the EMPULSE (empagliflozin in patients hospitalized with acute heart failure who have been stabilized) trial showed that empagliflozin decreased the risk of CVD or first events HF regardless of LVEF [77]

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