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1.4 Clinical manifestations The diagnosis of hypoglycemia has historically relied on Whipples triad, first described in 1938, which establishes three essential criteria: the presence of hypoglycemic symptoms, documented low plasma glucose levels, and resolution of symptoms following glucose administration

Key exclusion criteria include a history of hypersensitivity to monoclonal antibody drugs, treatment with any medication for obesity within 30 days before screening, and a diagnosis of diabetes requiring current use of any antidiabetic drug

That position reflects a practical clinical need because the 2025 joint advisory set protein intake at 1.2-1.6 g/kg/day for GLP-1 users, a level many patients will struggle to reach through reduced food intake alone

This means food stays in your stomach longer, leading to a sustained feeling of fullness

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