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That dissociation is the strongest practical argument for treating cerebrospinal fluid and plasma markers in these trials as exploratory readouts of target engagement rather than as stand-ins for benefit
They work by mimicking the hormone glucagon-like-peptide-1 (GLP-1)
The drug has anti-inflammatory effects, they said, and it also appears to reverse some of the changes in airways and the "hyper-responsiveness" of airways that asthma brings
