eli lilly oral glp-1 Lilly's pill may help people with Type 2 diabetes lose 'significant' weight, study finds The Food and Drug Administration

While one of the trials evaluated Orforglipron versus Dapagliflozin in 962 patients with type-2 diabetes inadequately controlled on Metformin, the other trial assessed Orforglipron versus placebo in 546 adults with type 2 diabetes and inadequate glycemic control with titrated insulin glargine

Yagi M, Kishimura Y, Okuda F, Ogura M, Ishizaki K, Takabe W, et al

This is not a step backward

Real-world data from healthcare databases have occasionally shown small increases in pancreatitis incidence, though these findings may reflect confounding factors such as obesity severity, rapid weight loss, or pre-existing pancreatic disease

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