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When stored under appropriate laboratory conditions, lyophilized Retatrutide is generally more stable than reconstituted solutions

doi: 10.2337/db10-0128

Renal protection with glucagon-like peptide type 1 receptor agonists In CVOTs of arGLP1 renal outcomes were prespecified as key secondary outcomes in 4 studies done with liraglutide, subcutaneous semaglutide, dulaglutide, and efpeglenatide,58,59,63,64 or were collected as safety parameters in other studies.60 Overall, the prevalence of CKD stage 3 in these studies was low (2030%) (Table 1)

Patients experiencing persistent vomiting or diarrhoea should maintain hydration and seek medical review, as there is a risk of acute kidney injury with severe gastrointestinal symptoms