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An investigational trial revealed that exosome microRNAs, miR-30d-5p and miR-126a-5p, and SIRT6 expression, were significantly reduced in diabetic HFpEF patients compared to non-diabetic patients [39, 40]

The visible symptoms of menopause, the hot flashes and the sleep disruption, are the acute manifestations of that withdrawal

Clinical outcomes (change in HbA 1c , weight, BMI, eGFR and cholesterol, compared with baseline) were recorded and analysed from 3 months to 3 years post index date

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