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Your starting weight, how well you tolerate side effects, whether youre training, and your protein intake all matter

According to FDA prescribing information, nausea affects approximately 44% of patients on Wegovy (weight management dose), while vomiting, diarrhea, constipation, and abdominal pain are also common, particularly during dose escalation

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Genetic variations in GLP-1 receptor sensitivity, FTO gene variants affecting appetite regulation, and MC4R pathway function create a 30-40% variance in treatment response between individuals

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