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doi: 10.7759/cureus.21536

A treatment still has to show an acceptable balance of efficacy, tolerability, manufacturing quality, and regulatory suitability before UK clinicians can use it routinely

Beraldo JI, Benetti A, Borges-Jnior FA, et al

Administrative hurdles and limited care pathways account for the remainder

In value-based care (like Medicare Advantage), documenting Z79.4 can contribute to HCC or RAF scoring, influencing payments and patient risk profiles
