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Magnesium glycinate (200-400 mg daily) may provide additional benefitstudies suggest magnesium deficiency worsens headache sensitivity

Patients experienced relief of symptoms upon discontinuation of the medication and a subset of patients experienced a recurrence of symptoms when restarting the same drug or a different DPP-4 inhibitor

Hyperglycemia induces skeletal muscle atrophy via a WWP1/KLF15 axis

Long-term safety data is still limited, and the novel glucagon-agonist component introduces uncertainties about long-term effects

Add Physical Activity [Staying active is key to maintaining muscle while losing weight on GLP-1 medications]( Strength training is particularly helpful in protecting lean tissue and breaking through weight-loss plateaus