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The Protein-Muscle Problem Research shows that up to 20 to 25 percent of weight lost on GLP-1 medications can come from muscle rather than fat

The recently initiated large-sized FLOW trial investigating the effects of semaglutide on hard renal outcomes in patients with DKD will provide clarity whether GLP-1 receptor agonists may reduce the burden of DKD in addition to their other beneficial metabolic and cardiovascular effects.

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Their potential for disease modification and symptom relief, particularly in specific phenotypes, supports their further exploration as part of a personalized treatment approach.

But for complex drugs like this, quality control is still improving