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Description
It is a major therapeutic target for type 2 diabetes and obesity
Increased PCDNAmTL was associated with better gait speed (p=0.012)
GLP-1 receptors are distributed throughout the central nervous system, including in the hypothalamus and the mesolimbic reward system the very dopamine-rich pathways involved in craving, motivation and emotional eating
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GLP-1RAs show modest SBP reductions (1.85.1 mmHg) and minimal DBP effects (~0.5 mmHg), though tirzepatide shows greater efficacy (~10.6 mmHg) in select populations
