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This article reviews the efficacy and safety of different strategies to initiate and intensify basal insulin, with focus on new fixed ratio combinations of basal insulin with GLP-1 RAs available for use in a single injection pen (insulin degludec/liraglutide and insulin glargine/lixisenatide).
Explore GLP-1 trends as users foresee long-term use and increased spending on clothing, groceries, and more

As demand for GLP-1 medications like Ozempic and Wegovy surges, many are turning to medspas for accessbut that convenience comes with risks

Consequently, GLP-1 that is secreted by intestinal L-cells is rapidly degraded by dipeptylpeptidase-4 (DPP-4) in the endothelium of the portal circulation and in the liver, as well as by a soluble circulating moiety of DPP-4