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GLP-1s are only approved for the treatment of Type 2 diabetes and weight management, but the added dermatologic benefits indicate overlap between the systemic pathways involved metabolic disease and chronic inflammation

What happens to GLP-1 in type 2 diabetes

Approximately 60% of patients with HF with preserved ejection fraction (HFpEF) also live with obesity (Morgen et al
GLP-1 also blocks glucagon secretion
