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The information is publicly visible: Because anyone can access FAERS, media coverage, or social media chatter can amplify a perceived link, which in turn may drive more selfreports, reinforcing the appearance of an association

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doi: 10.3389/fcdhc.2025.1687149 Received 20 August 2025 Revised 27 October 2025 Accepted 19 November 2025 Published 08 December 2025 Volume 6 - 2025 Edited by Didac Mauricio, University of Vic - Central University of Catalonia, Spain Reviewed by Emmanuel Sindato, University of Dodoma, Tanzania Sittisak Honsawek, Chulalongkorn University, Thailand Updates Copyright 2025 Vo and Lam

On the other hand, peripheral administration of pharmacological doses of exogenous radiolabelled GLP1 leads to detectable amounts found in the circumventricular organs of the brain, which are characterised by a leaky bloodbrain barrier (BBB) (Orskov et al., 1996)

Common side effects can include nausea, vomiting, constipation, and diarrhea