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Afterward, they are stored in the gallbladder, released into the intestinal lumen after a meal, and further metabolized by the gut microbiota into secondary bile acids

Possible Side Effects Tirzepatide may cause: Nausea Constipation Diarrhea Decreased appetite Temporary fatigue Gradual dose titration improves tolerability

But translation to humans at subtherapeutic doses

GLP-1 receptor agonists improve insulin sensitivity and stabilize blood glucose levels throughout the body

Chen XW, He ZX, Zhou ZW, Yang T, Zhang X, Yang YX, et al
