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In cases of refractory ascites or hepatorenal syndrome, which often coincide with hypotension, RAAS inhibitors and diuretics should be used judiciously, with close monitoring of renal function and electrolyte balance

ClinicalTrials.gov REDEFINE 1 - Cagrilintide and Semaglutide in Adults with Overweight or Obesity

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A 2023 analysis of GLP-1 agonist effects found that patients often reported mood improvements coinciding with weight loss and metabolic stabilization
