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Description
Clean the skin with alcohol and let it dry

Potential causes include medication interactions (particularly with diabetes medications), thyroid dysfunction, severe insulin resistance, genetic factors affecting GLP-1 receptor function, or gastrointestinal issues preventing medication absorption

Skip it and you risk contaminating a vial worth hundreds of dollars

Single and dual agonists The fundamental difference between these two molecules is that semaglutide is a GLP-1 agonist, i.e., it has a strong structural similarity (95%) with this hormone and specifically activates its receptor, while tirzepatide is a dual agonist, i.e., it has a hybrid structure that allows it to activate both GLP-1 and GIP receptors (Figure 2)

Keep vials in the refrigerator vegetable drawer or another dark location rather than on a brightly lit shelf
