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Current trials also exclude people with diabetes, recent heart problems, and eating disorders, which may indicate future contraindications once approved

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The most common codes are PA-NOT-MET, NF (non-formulary), STEP-REQ (step therapy required), BMI-NOT-MET, MEDICARE-EXCL (Medicare weight-loss exclusion), and EMP-EXCL (employer carve-out)

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Data in C N were analyzed using repeated-measure 2-way ANOVA with Benjamini, Krieger, and Yekutieli post hoc test (FDR = 0.05) to compare individual time points

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NSAIDs combined with GLP-1 agonists carry increased risk of pancreatitis and kidney stress during rapid weight loss

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