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How GLP-1 Receptor Agonists Cause Weight Loss By binding to the GLP-1 receptor, GLP-1 RAs mimic the effects of having eaten and released GLP-1

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On average, patients randomised to receive 15mg of Mounjaro the maximum dose experienced a lowering of their haemoglobin A1c (HbA1c) level, which measures blood sugar control, by 1.6% more than placebo when used as stand-alone therapy, and 1.5% more than placebo when used in combination with a long-acting insulin

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