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Background Hyperkalemic Periodic Paralysis (hyperPP) is an autosomal dominant genetic disorder where high extracellular potassium is associated with skeletal muscle depolarization and both flaccid muscle weakness as well as delayed muscle relaxation that can lead to myotonia and myopathy

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The 13 states that maintain coverage impose strict restrictions including BMI thresholds over 30, prior authorization requirements, and step therapy mandating patients first try diet, exercise, and cheaper alternatives