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The modulatory effects of combined therapy with GLP-1RAs and other drugs on tumor risk As GLP-1RAs continue to see expanding clinical application, it is imperative that clinicians give careful consideration to the potential adverse effects linked to combination therapies

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The first-in-class dual GIP/GLP-1 RA tirzepatide, available as a once-weekly subcutaneous injection, generates even larger reductions in HbA 1c and weight than semaglutide