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This study could provide valuable insights for the design of clinical trials involving GLP-1R-based agonists and enhance our understanding of this category of medications

patents with priority dates after approval are of particular interest because of their potential to extend market exclusivity since patent terms are generally tied to priority dates

This triggers an inflammatory response within the skin, driven predominantly by pro-inflammatory cytokines such as IL-1and TNF-, along with mediators from activated Th1 and Th17 helper cells (including IFN- and IL-17), and effector mechanisms involving neutrophils, macrophages, and plasma cells [17,18,19]

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Evaluated by sandwich enzyme immunoassay, using the Enzyme-linked Immunosorbent Assay Kit from Cloud-Clone Corp