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Combination of oligofructose and metformin alters the gut microbiota and improves metabolic profiles, contributing to the potentiated therapeutic effects on diet-induced obese animals
Although numerous peptides participate in this axis, glucagon-like peptide-1 (GLP-1) plays a central role
Acknowledgements This work was supported by the National Institute for Health and Care Research (NIHR) Leicester Biomedical Research Centre
A randomized clinical trial of once-weekly exenatide for alcohol use disorder published in JAMA Psychiatry (2022) did not meet its primary endpoint of reducing heavy drinking days in the overall study population
Diabetes Care 37 , 21412148 (2014)
