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Additionally, the cardiac magnetic resonance substudy of the SUMMIT trial revealed that compared with placebo, tirzepatide treatment of obese HFpEF patients reduced the LV mass and paracardial adipose tissue volume, with the changes in the LV mass paralleling the degree of weight loss [166]

In contrast, male patients exhibited a longer median onset time for these conditions when using semaglutide and tirzepatide

Strengths of the study include the randomized design and that changes in bone health were assessed at sites of clinical relevance for fragility fractures (ie, the hip, lumbar spine, and distal forearm)

Exenatide was approved by the US FDA in 2005 and by the European Medicines Agency (EMA) in 2006
Semaglutide We offer up to 2mg/week (as medically appropriate) for an additional $100 per month