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Researchers Call for Further Investigation Lead author Amin Ariaee, a PhD candidate at Adelaide University, said the rapid expansion of oral obesity treatments that utilize SNAC makes it important to fully understand how every ingredient in these medications affects the body over time

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Diarrhea, constipation, and fatigue are also common

What makes retatrutide stand out is the apparent dose-dependence: higher doses were linked to a greater likelihood of nausea and vomiting, while lower starting doses were associated with a gentler side effect profile

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