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Early data show that if a patient has been highly successful with GLP-1s, they are likely to be highly successful with weight-loss surgery because they work through many of the same mechanisms

The PlexusDx Precision Peptide Genetic Test ($99 add-on after your first month) analyzes variants in GLP1R, GIPR, FTO, and MC4Rgenes that directly influence how your body responds to GLP-1 therapy and regulates appetite

My advice for patients is to be entirely open and honest with your physicians and to have high expectations of them

Despite some studies that have been published with 4 years of follow-up, more time will be needed to better understand whether the continued use of SMG may lead to long-term adverse effects

However, accessing these therapies often requires navigating complex prior authorization (PA) processes, which can delay treatment and increase administrative burden