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Conclusion GLP-1 medications present cost challenges, with monthly expenses often exceeding $1,000 monthly without insurance coverage
Further investigation revealed that the use of fatty di-acids longer than 14 carbons attached via Glu resulted in loss of activity, while the use of mono-acids of up to 16 carbons (palmitate) retained activity, as shown in Table 1
Retatrutide (LY3437943) is an investigational peptide currently undergoing clinical evaluation
2022;377: e068882
