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MARKET TRENDS & DRIVERS Rising Global Prevalence of Type 2 Diabetes and Obesity Drives Demand for GLP-1 Analogues Improved Cardiovascular Outcomes Data Strengthens Business Case for GLP-1 as First-Line Therapy Launch of Once-Weekly and Oral Formulations Throws Spotlight on Patient Convenience and Compliance Expanded Indications for Weight Management Create Cross-Sector Market Growth Strong Pipeline Activity and Strategic Partnerships Fuel Innovation and Market Entry Government and Insurance Reimbursement Policies Accelerate Global Access to GLP-1 Drugs High Clinical Efficacy and Low Hypoglycemia Risk Drive Physician Preference for GLP-1 Therapies Integration with Digital Health Platforms and Remote Monitoring Enhances Adherence M&A and Licensing Activity Among Pharma Giants Expand Competitive Landscape and Reach Emerging Research in Neurodegenerative and Cardiometabolic Diseases Broadens Future Applications Direct-to-Consumer Campaigns and Social Awareness Spur Patient-Driven Demand Supply Chain and API Manufacturing Investments Ensure Scalability and Global Market Coverage 4

From $149/Month Pricing based on a 45 month treatment program

Results Exposure to GLP1-RA in the first trimester was not associated with a risk of major birth defects when compared with diabetes (2.6% vs 2.3%

Painter NA, Morello CM, Singh RF, McBane SE

Rena, G., Hardie, D