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Neuropharmacology (2021)
Theres a strong chance youve heard the term associated with psychedelics, like LSD or psilocybin mushrooms
Effects: By activating GLP-1 receptors, Tirzepatide increases insulin secretion in response to meals, reduces glucagon release (which helps lower blood sugar), and slows gastric emptying (promoting feelings of fullness)
Body-weight reduction in obesity (phase 2) A 48-week randomised, double-blind, placebo-controlled phase 2 trial in the New England Journal of Medicine studied retatrutide in 338 adults with obesity
Chronic constipation requiring ongoing intervention deserves comprehensive assessment rather than indefinite self-management
