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The FTC report, the academic literature, and even some PBM-commissioned studies acknowledged the opacity problem

While other trials did not include proteomic analysis, the findings of metabolic improvements and weight loss indirectly suggest alterations in key metabolic proteins 34,52 (Table 3)

As a result, we anticipate ongoing supply disruptions and are aware that some patients will continue having difficulty filling Wegovy prescriptions. Novo-Nordisk saw an over 30% increase in sales of Wegovy since the beginning of 2023, creating the shortage

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For patients already using a GLP-1 receptor agonist but needing stronger blood sugar and weight control, tirzepatide may offer added benefits because of its dual-action mechanism