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Doses of liraglutide previously shown to have efficacy in AD and PD mouse models were used

Despite efficacy, GLP-1 RAs are associated with adverse reactions across multiple organ systems

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Among the individual GLP-1RAs assessed, the largest reductions in CV risk, HbA1c, and weight outcomes were observed with combination therapy with SGLT2i and once weekly semaglutide for T2D
