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Protocol Used: Started at 2mg weekly for 4 weeks, increased to 4mg for weeks 5-8, then 8mg from week 9 onward

In intact murine islets, blockade of N-type Ca 2+ channels with -conotoxin, but not L-type Ca 2+ channels using nifedipine, abolishes low glucose (1 mM) stimulation of glucagon secretion and blunts the GLP-1-mediated inhibitor effects

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Campbell, T

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