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For example, a study on liraglutide found it produced greater weight loss compared to metformin, with favorable impacts on menstrual regularity

[11] Smits MM, et al

These discrepancies may arise from differences in sample sizes, study designs, and the power of individual datasets to detect genetic associations

Individuals With Obesity and COVID-19: A Global Perspective on the Epidemiology and Biological Relationships

Given the pilot nature of the trial, the (relatively) small degree of weight loss achieved, and the well-described association between weight loss and fracture risk, we believe that further exploration into this increasingly relevant question is warranted