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Description
Although CNO is often used as the inert ligand for DREADDs, studies show minimal, yet significant, reverse metabolism to clozapine, an active metabolite which could bind to non-DREADD receptors and produce off-target effects on behavior 31
Patients in UT Southwesterns Weight Wellness Program often exceed these weight loss results
All weight loss leads to both fat and muscle loss, which can be a concern, especially in people who are already frail
doi: 10.1073/pnas.86.11.3953
If you experience any suspected side effects, you can report them through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)
