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doi: 10.1128/mSystems.00985-20 116 ShiM.YueY.MaC.DongL.ChenF

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The upregulation of the expression and activity of transcription factor pancreatic-duodenum homeobox-1 (PDX-1) and its increased activity also promote insulin transcription and biosynthesis via a PKA-mediated mechanism (Wang et al., 1999, 2001)