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Rodents have substantially higher densities of GLP-1 receptors on thyroid C-cells compared to humans, and their thyroid physiology differs markedly from that of humans

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Since GLP-1 weight-loss medications exploded in popularity a few years ago, Chitra Ganta, MD, a geriatrician at the Cleveland Clinic, has seen a flood of interest from her patients

If ePA adoption is uneven (e.g

Weight loss outcomes vary by agent and dose: high-dose semaglutide (2.4mg/Wegovy) has shown mean weight reductions of approximately 15% in the STEP clinical trials, while liraglutide (3mg/Saxenda) typically achieves 5-8% weight loss