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Among the marketed large molecule injectable GLP-1 agonists, semaglutide, apart from weight-loss, is being studied for kidney disease and tirzepatide (a dual GLP-1 and GIP receptor agonist) is being evaluated for sleep apnea in Ph 3 clinical trials

Bloating is a common digestive side effect reported by people starting semaglutide therapy
Bone is a highly dynamic organ that changes with the daily circadian rhythm

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