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[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Neuen BL, Ohkuma T, Neal B, Matthews DR, de Zeeuw D, Mahaffey KW, et al
It lets tolerability settle so the next increase lands on a calmer gut
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J Biol Chem 1992;267:74025.PubMed 8
In June 2025, the World Health Organisation issued a warning about this risk
