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Mood symptoms Animal studies, case reports, and a meta-analysis of RCTs of GLP-1 RAs suggest that these medications might help with depression (Chen X et al, Am J Geriatr Psychiatry 2024;32(1):117127)

doi: 10.1016/j.molmet.2024.101960

Darpo B, Sager P, Macconell L, Cirincione B, Mitchell M, Han J, Huang W, Malloy J, Schulteis C, Shen L, Porter L

GLP-1 weight loss programs are ideal for adults who: Struggle with appetite control or plateaued weight loss Have difficulty managing blood sugar levels Want to lose weight safely under medical supervision Prefer a structured, science-based approach over crash diets Your provider will help determine whether semaglutide-based treatment is the right fit for you

However, the rate of patient discontinuation due to adverse effects from this treatment was higher than liraglutide side effects [50]