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The diabetes-versus-obesity nuance It is worth noting that in the REDEFINE 2 study of CagriSema in people with type 2 diabetes, the weight-loss magnitude was somewhat lower than in the non-diabetes REDEFINE 1 population a reminder that efficacy (and by extension any downstream liver benefit) is population-dependent, and that MASH patients, who frequently have diabetes, may respond differently than the leaner-metabolism trial populations

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Patients with diabetes should discuss medication adjustments with their healthcare provider and monitor blood glucose levels, particularly when starting or increasing their Wegovy dose

[DOI] [PubMed] [Google Scholar] 99.Newgard C.B., An J., Bain J.R., Muehlbauer M.J., Stevens R.D., Lien L.F., Haqq A.M., Shah S.H., Arlotto M., Slentz C.A., et al

Retrieved from Trinh, H., Donovan, A., McAdam-Marx, C