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GLP-1 is a hormone released after eating that increases insulin secretion, slows down how fast the stomach empties, and reduces hunger cues

GLP-1 medications mimic a natural hormone that regulates blood glucose, slows gastric emptying, and acts on brain appetite centres

Building upon these promising findings, tirzepatide was investigated in cardiometabolic HFpEF patients in the SUMMIT HFpEF trial with a longer follow-up of 104 weeks 37

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16 L of this pooled probe mixture was combined with 40 L PEG-4000 (50% w/v), 40 L T4 DNA ligase buffer, 72 L water, and 2 L T4 DNA Ligase (30 U/L, Thermo Fisher)