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Description
May 2022

Next step: larger, well-powered trials in knee OA that prioritize patient-centered outcomes (pain, function, imaging, and time to joint replacement), plus equitable access so these benefits are not limited to the few

Why does hunger come back after GLP-1 treatment

Patients often describe this as quieter food thoughts

In addition to the well-known effects of GLP-1 and GLP-1 RA in improving insulin sensitivity and reducing body weight, at central levels, GLP-1 and GLP-1 RA might exert regulating effects on GhRH release, and on concomitant gonadotropin secretion, likely by activating the kisspeptin hypothalamic system, a key regulator of the pulsatile release of GnRH from GnRH neurons
