what glp-1 Updates for Employers: Demand, Shortages, and Cost GLP-1 Receptor Agonists as Treatments

In HFpEF, the effects of the drugs on cardiac function and structure have not yet been investigated

They just dont want it anymore

You cant have untreated depression or anxiety

When compared with placebo or other therapies, GLP-1 agonists were associated with an increased risk of biliary disease [23]: Overall biliary disease: RR 1.37(95% CI 1.231.52) Cholelithiasis: RR 1.27 (95% CI 1.101.47) Cholecystitis: RR 1.36 (95% CI 1.141.62) Mechanisms: Reduced gallbladder motility Rapid weight loss increased cholesterol saturation and gallstone formation

Paxlovid (nirmatrelvir/ritonavir) Disease area(s): Infectious diseases (antivirals) Manufacturer(s): Pfizer 2024 Sales (USD): $5.72 billion Why it sold so well: In 2024, Pfizers COVID-19 antiviral treatment, Paxlovid, generated $5.72 billion in global revenue, making it the companys third-highest-selling product for the year