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(Guangzhou, China)

Mechanistic studies indicate that GLP-1RAs suppress the perception of all basic taste modalities, probably through combined actions in the brainstem and vagal modulation, although paradoxical cases of sweet hypersensitivity have been documented in specific populations (162)

While these drugs are widely praised for helping people lose significant weight, the study found that physical activity did not increase alongside that weight lossas many might expect