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Description
Semaglutide is recommended as an option: As monotherapy when metformin is contraindicated or not tolerated, or In dual or triple therapy combinations when a GLP-1 receptor agonist is appropriate (for example, when further glucose control is needed and weight loss would be beneficial, or when other treatments are unsuitable)
Novolog, in its turn, is also approved for adults with type 1 and type 2 diabetes and children (generally age 2 years and older) with type 1 diabetes

While not required for treatment, the test often pays for itself through faster, more targeted weight loss outcomes and lower total treatment duration costs

Hogg, E
This effect is consistent with what has been observed with other GLP-1 based compounds and is thought to reflect a combination of weight-mediated reduction in vascular resistance and direct vascular effects of GLP-1 receptor activation
