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Participants exhibited reduced neural response to high-calorie food images, suggesting a shift in food-related attention and motivationmechanisms that may contribute to sustained appetite suppression and reduced caloric intake in research contexts

Injectable versions require only one subcutaneous shot per week, reducing the mental load of medication management

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88.8% of Phase 2 participants on the 12mg dose completed the full 48-week trial

Patients with pre-existing diabetic retinopathy should attend regular eye screening as rapid improvement in glucose control may temporarily worsen retinopathy