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These changes are typically related to the weight loss process itselfincluding dietary modifications, dehydration from gastrointestinal side effects, or mild ketosisrather than a direct pharmacological effect of the medication

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(A review of methods for detecting peptide drugs in biological matrices that provides insight into the technical challenges of measuring such compounds.) Schnell, O., Schumacher, A., & Menger, M

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Lake BB, Menon R, Winfree S, et al