slow responders to glp 1 New *promising* study for GLP1 slow/non-responders! #joinfridays #glp1 If semaglutide does not work

This slows after 24 weeks as the body stabilizes fluid levels

Some GLP1R/GIPR co-agonists are in clinical development for T2DM treatment

1 o Investigators were encouraged to optimize standard-of-care treatment for T2D, CKD, and CV risk management according to local treatment practice

GLP-1 medications may help support appetite control and glucose balance by mimicking the bodys natural signals related to fullness and digestion, which may help some patients feel satisfied with smaller portions

Korol SV, Jin Z, Jin Y, Bhandage AK, Tengholm A, Gandasi NR, et al (2018) Functional characterization of native, high-affinity GABAA receptors in human pancreatic cells